https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45424 Wed 22 Mar 2023 18:37:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43504 Wed 21 Sep 2022 10:29:28 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34234 Wed 20 Feb 2019 15:55:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33810 ShSUT1 in sucrose mobilisation and storage in sugarcane was investigated by employing RNAi technology to reduce the expression of this gene. Transcript profiling in non-transformed plants showed an alignment between expression and sucrose concentration, with strongest expression in source leaves and increasing expression through the daylight period of a diurnal cycle. Five transgenic plant lines were produced with reduced ShSUT1 expression ranging from 52 to 92% lower than control plants. Differential suppression of ShSUT1 sequence variants in the highly polyploid sugarcane genome were also investigated. Amplicon sequencing of the ShSUT1 variants within the transgenic lines and controls showed no preferential suppression with only minor differences in the proportional expression of the variants. A range of altered sugar, fibre and moisture contents were measured in mature leaf and internode samples, but no phenotype was consistently exhibited by all five transgenic lines. Phenotypes observed indicate that ShSUT1 does not play a direct role in phloem loading. ShSUT1 is likely involved with retrieving sucrose from intercellular spaces for transport and storage.]]> Wed 16 Jan 2019 14:37:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46486 individual and community empowerment in smoking cessation during pregnancy studies with Aboriginal women. Three interventions were found in published and grey literature. Elements of individual empowerment were embedded in all interventions. Interventions considered barriers for Aboriginal women to quit smoking and areas for capacity building. Interventions used health education resources. There was limited reporting of community empowerment domains. Aboriginal ethics and capacity building was the only criterium addressed by all studies. Interventions are incorporating individual empowerment, but seldom report community empowerment. The development of reporting guidelines or extensions of current guidelines would be beneficial to set a consistently high standard reporting across Aboriginal health interventions, similar to the work conducted to develop the extension of Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Equity (PRISMA-E) for health equity in systematic review reporting. Reporting empowerment domains would reflect the government priority of empowerment to improve Aboriginal health, as well as enhancing knowledge translation into practice.]]> Wed 13 Mar 2024 09:40:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44292 Wed 13 Mar 2024 08:56:20 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53579 Wed 13 Mar 2024 07:48:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19799 Wed 11 Apr 2018 15:56:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30383 Wed 11 Apr 2018 15:20:36 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4721 Wed 11 Apr 2018 11:31:55 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12370 Wed 11 Apr 2018 11:10:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38906 Wed 02 Mar 2022 12:50:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34306 Tue 26 Feb 2019 16:56:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44947 Tue 25 Oct 2022 10:50:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44935 Tue 25 Oct 2022 10:36:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35291 Tue 23 Jul 2019 09:12:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32500 Tue 12 Jun 2018 09:15:12 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44317 Tue 11 Oct 2022 16:19:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33553 Tue 03 Sep 2019 18:31:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38549 Tue 02 Nov 2021 14:42:59 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45559 n = 27) was characterised by immunohistochemistry and by mRNA analyses. Stroma was identified by immunostaining of stromal matrix collagen type I and proliferating cells were identified by Ki67 expression. The cortical and medullar volume expanded across gestation, with the rate of cortical expansion slowing over time. During gestation, the proportion of stroma in the cortex and total volume in the cortex significantly increased (P < 0.05). The proliferation index and numerical density of proliferating cells in the stroma significantly decreased (P < 0.05), whereas the numerical density of cells in the stroma did not change (P > 0.05). The expression levels of 12 genes out of 18 examined, including osteoglycin (OGN) and lumican (LUM), were significantly increased later in development (P < 0.05) and the expression of many genes was positively correlated with other genes and with gestational age. Thus, the rate of cortical stromal expansion peaked in early gestation due to cell proliferation, whilst late in development expression of extracellular matrix genes increased.]]> Tue 01 Nov 2022 13:09:00 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50178 Tue 01 Aug 2023 11:01:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36197 Sminthopsis crassicaudata). Forty-eight randomly selected females were treated with 5 or 10 mgkg^-1 Lucrin Depot (n = 24 per dose). Eighteen females per treatment had their reproductive activity scored at 4, 8, 12 and 16 weeks using two ovarian (Graafian follicle and corpus luteum status) and two reproductive tract (uterine and vaginal muscularity and vascularity) parameters that formed a reproductive activity score. Six females per treatment were paired with a male at 4 weeks. Fertility was assessed between 8 and 16 weeks by pouch check, and thereafter by dissection. The effects of the 5 and 10 mgkg^-1 doses were statistically equivalent. Females showed suppression at 4-8 weeks, an increase in reproductive activity at 8-12 weeks and all were cycling normally at 16 weeks. Six pouch young were born at 12 weeks to two females treated with the 5 mgkg^-1 dose. Nine embryos were recovered at 16 weeks from two females treated with the 10 mgkg^-1 dose. In conclusion, Lucrin Depot can suppress breeding, and fertile mating can occur in subsequent cycles in the dunnart. There is potential for Lucrin Depot to be used as an assisted breeding tool, but it may need to be combined with ovarian stimulation treatment to achieve practical levels of synchronisation in the fat-tailed dunnart.]]> Thu 27 Feb 2020 13:33:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46487 Thu 24 Nov 2022 11:52:53 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34722 Thu 17 Mar 2022 14:34:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33819 0) to 1% precision, and the growth rate of structure to 5%; (ii) to make the most extensive map yet constructed of the total mass distribution and motions in the local Universe, using peculiar velocities based on improved Fundamental Plane distances, which will enable sensitive tests of gravitational physics; and (iii) to deliver a legacy sample of low-redshift galaxies as a unique laboratory for studying galaxy evolution as a function of dark matter halo and stellar mass and environment. The final survey, which will be completed within 5 yrs, will consist of a complete magnitude-limited sample (i ⩽ 17) of about 1.2 × 10⁶ galaxies supplemented by an extension to higher redshifts and fainter magnitudes (i ⩽ 18.1) of a luminous red galaxy sample of about 0.8 × 10⁶ galaxies. Observations and data processing will be carried out remotely and in a fully automated way, using a purpose-built automated ‘virtual observer’ software and an automated data reduction pipeline. The Taipan survey is deliberately designed to maximise its legacy value by complementing and enhancing current and planned surveys of the southern sky at wavelengths from the optical to the radio; it will become the primary redshift and optical spectroscopic reference catalogue for the local extragalactic Universe in the southern sky for the coming decade.]]> Thu 17 Jan 2019 11:26:10 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20835 Diabetes Research and Clinical Practice, Diabetes Care, Diabetic Medicine, Population Health Management, Rural and Remote Health, Australian Journal of Primary Health, PLoS Medicine, Medical Journal of Australia, BMC Health Services Research, BMC Public Health, BMC Family Practice) and Commonwealth and state government health websites was undertaken to acquire Australian studies of diabetes workforce models published 2005–13. Various diabetes workforce models were examined, including ‘one-stop shops’, pharmacy care, Aboriginal services and telephone-delivered interventions. The quality of evidence was evaluated against several criteria, including relevance and replication, strength of evidence, effect size, transferability and representativeness, and value for money. Results: Of the 14 studies found, four were randomised controlled trials and one was a systematic review (i.e. Level II and I (best) evidence). Only three provided a replicable protocol or detailed intervention delivery. Eleven lacked a theoretical framework. Twelve reported significant improvements in clinical (patient) outcomes, commonly HbA1c, cholesterol and blood pressure; only four reported changes in short- and long-term outcomes (e.g. quality of life). Most studies used a small or targeted population. Only two studies assessed both benefits and costs of their intervention compared with usual care and cost effectiveness. Conclusions: More rigorous studies of diabetes workforce models are needed to determine whether these interventions improve patient outcomes and, if they do, represent value for money. What is known about the topic?: Although health systems with strong primary care orientations have been associated with enhanced access, equity and population health, the primary care workforce is facing several challenges. These include a mal-distribution of resources (supply side) and health outcomes (demand side), inconsistent support for teamwork care models, and a lack of enhanced clinical inter-professional education and/or training opportunities. These challenges are exacerbated by an ageing health workforce and general population, as well as a population that has increased prevalence of chronic conditions and multi-morbidity. Although several policy directions have been advocated to address these challenges, there is a lack of high-quality evidence about which primary care workforce models are best (and which models represent better value for money than current practice) and what the health effects are for patients. What does this paper add?: This study demonstrated several strengths and weaknesses of Australian diabetes models of care studies. In particular, only five of the 14 studies assessed were designed in a way that enabled them to achieve a Level II or I rating (and hence the ‘best’ level of evidence), based on the NHMRC’s (2000, 2001) frameworks for assessing scientific evidence. The majority of studies risked the introduction of bias and thus may have incorrect conclusions. Only a few studies described clearly what the intervention and the comparator were and thus could be easily replicated. Only two studies included cost-effectiveness studies of their interventions compared with usual care. What are the implications for practitioners?: Although there has been an increase in the number of primary care workforce models implemented in Australia, there is a need for more rigorous research to assess whether these interventions are effective in producing improved health outcomes and represent better value for money than current practice. Researchers and policymakers need to make decisions based on high-quality evidence; it is not obvious what effect the evidence is having on primary care workforce reform.]]> Thu 16 Jul 2020 10:20:24 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40022 Tyto alba delicatula) and the threatened eastern grass owl (Tyto longimembris) are predators that may have occupancy patterns linked with prey abundance. It is important to identify the resources that cause increases in primary prey items to further understanding of the ecology of these species. Here I test the hypothesis that grass seeds cause increased abundances of wetland-dwelling house mice (Mus musculus) in austral summer, and identify a wetland monocot that provides a food recourse to achieve this effect, as well as report eastern grass owl and barn owl observations. A 2.6 ha wetland area (on Kooragang Island, New South Wales) was surveyed almost weekly to quantify abundance of prey items from September to April for three years (2016–2019). Typha sp. (a monocot) had flowering periods that coincided with increases in house mouse observations (n = 90 in flowering, n = 2 in non-flowering), where 22% were detected feeding on Typha flowers/seeds or fleeing from flower stalks. Eastern grass owls were only observed during a Typha flowering period (n = 3). These observations confirmed the original hypothesis and led to the formulation of another hypothesis: wetland occupancy by eastern grass owls is influenced by Typha flowering. Future studies should aim to test this hypothesis and identify other wetland plants that provide an important food source for wetland-dwelling rodents.]]> Thu 14 Jul 2022 14:35:11 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34112 Thu 14 Apr 2022 11:04:35 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36844 Thu 09 Jul 2020 13:15:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38165 2/microwave-mediated approach afforded access to pure material, collected by cooling and filtration after 20-min microwave irradiation at 120°C. A total of 41 analogues were prepared in isolated yields of 17–99 %. This process was highly tolerant of aliphatic, aromatic, heterocyclic, and acyclic aldehydes, but furan, pyrrole, and thiophene aldehyde reactivity correlated with propensity towards electrophilic addition and/or Diels–Alder addition. As a result, thiophene afforded high yields (80 %) whereas pyrrole carboxaldehyde failed to react. With simple cinnamaldehydes, and in the SbCl₃-mediated reaction, and with α,β-unsaturated aldehydes the equivalent quinazolin-4(3H)-ones, and not the 2,3-dihydroquinazolin-4(1H)-ones, was favoured.]]> Thu 05 Aug 2021 11:45:40 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36843 Thu 04 Nov 2021 10:39:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38382 Thu 02 Sep 2021 15:23:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31338 Inha-KO) mice, which feature Sertoli cell tumours in adulthood. Here, we identified the developmental windows by which adult Sertoli cell tumourigenesis is most FSH sensitive. FSH was suppressed for 7 days in Inha-KO mice and wild-type littermates during the 1st, 2nd or 4th week after birth and culled in the 5th week to assess the effect on adult Sertoli cell development. Tumour growth was profoundly reduced in adult Inha-KO mice in response to FSH suppression during Weeks 1 and 2, but not Week 4. Proliferative Sertoli cells were markedly reduced in adult Inha-KO mice following FSH suppression during Weeks 1, 2 or 4, resulting in levels similar to those in wild-type mice, with greatest effect observed at the 2 week time point. Apoptotic Sertoli cells increased in adult Inha-KO mice after FSH suppression during Week 4. In conclusion, acute FSH suppression during the 1st or 2nd week after birth in Inha-KO mice profoundly suppresses Sertoli cell tumour progression, probably by inhibiting proliferation in the adult, with early postnatal Sertoli cells being most sensitive to FSH action.]]> Sat 24 Mar 2018 08:44:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31274 Sat 24 Mar 2018 08:44:31 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1047 Sat 24 Mar 2018 08:32:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1613 Sat 24 Mar 2018 08:30:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:1233 Sat 24 Mar 2018 08:28:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14523 Sat 24 Mar 2018 08:19:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5121 Sat 24 Mar 2018 07:48:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:5246 Sat 24 Mar 2018 07:44:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25528 -3) were used as fluidised particles. Three different combinations of particle size pairs of both equal and unequal mass ratios were used using a constant liquid (water) superficial velocity of 0.17 ms^-1 in all the cases. Numerically, a two dimensional Eulerian-Eulerian (E-E) CFD model incorporating kinetic theory of granular flow (KTGF) was developed to predict the bed expansion behaviour. It was observed that complete bed segregation occurred when the difference between the solid particle diameters was higher while lower difference in particle diameters led to partial bed segregation. The CFD model also predicted these behaviours which were in good agreement with the experimental data.]]> Sat 24 Mar 2018 07:26:07 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3280 Sat 24 Mar 2018 07:22:25 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3281 Sat 24 Mar 2018 07:22:25 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3144 Sat 24 Mar 2018 07:18:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24442 Sat 24 Mar 2018 07:17:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23596 Sat 24 Mar 2018 07:13:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46613 Cladocopium sp. (syn. clade C3) within the host coral Acropora aspera during exposure to thermal stress. Exposure to temperatures between 2 and 3°C below the bleaching threshold, equating to 2-degree heating weeks (DHWs), results in changes to the symbiont cell morphology and cell division rates. Once corals were exposed to 4 DHWs, over 90% of the symbiont cells showed signs of degradation. Although sub-bleaching thermal stress is not sufficient to trigger bleaching alerts at an ecological scale, this stressor substantially affects the coral symbiosis. It is therefore vital that we begin to quantify how sub-bleaching thermal stress affects the fitness of Symbiodiniacea populations, their coral hosts and subsequently reefs worldwide.]]> Mon 28 Nov 2022 10:36:55 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34258 Mon 25 Feb 2019 11:39:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55695 Mon 17 Jun 2024 15:05:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36143 Mon 17 Feb 2020 14:47:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38226 75 μm), was 13.4% higher under CT, but mesoporosity (30–75 μm) was 9.6% higher under NT. The vertical distributions of root biomass and root architecture measurements (i.e. root length density) in undisturbed soil cores were 9.6% higher under the NT and 8.7% higher under the CT system respectively. These results suggest that low soil disturbance under the continuous NT system may have encouraged accumulation of more root biomass in the top 100 mm depth, thus developing better soil structure. Overall, µXCT image analyses of soil cores indicated that this tillage shift affected the soil total carbon, due to the significantly higher soil-pore (i.e. pore surface area, porosity and average pore size area) and root architecture (i.e. root length density, root surface density and root biomass) measurements under the CT system.]]> Mon 16 Aug 2021 15:47:54 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35587 Mon 09 Sep 2019 10:25:46 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39061 Mon 02 May 2022 16:54:05 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27363 Fri 25 Mar 2022 15:38:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51915 0.77, P < 0.0001). At this site, SOC concentration appears related to erosion and deposition patterns. Conclusion: The hillslope distribution of 137Cs and 210Pbex were very similar, indicating that both tracers were viable in this environment (r = 0.9, P < 0.0001). The different origins and half-lives of 137Cs and 210Pbex also demonstrate that the patterns of erosion and deposition are consistent at decadal time scales. Implications: The use of 210Pbex provides an alternative method for understanding erosion and deposition patterns as well as that of SOC, given that the viability of 137Cs (half-life of 30.1 years) is now questionable due to no new replenishment.]]> Fri 22 Sep 2023 12:03:04 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39724 Senecio (Asteraceae), where both threatened and invasive species occur within Australia. In this study, propagule geometry, settling velocity and dispersal potential for two range-restricted and threatened native taxa (S. linearifolious var. dangarensis Belcher ex I.Thomps., S. spathulatus var. attenuatus I.Thomps.) are contrasted with four native taxa that occupy wider ranges (S. amygdalifolius F.Muell., S. l. var. arachnoideus I.Thomps., S. l. var. macrodontus (DC.) I.Thomps., S. pinnatifolius A.Rich. var. pinnatifolius) and one introduced, wide-ranging species (S. madagascariensis Poir.). Differences were found in settling velocity and propagule morphology across all taxa. Based on propagule morphology, S. amygdalifolius has the greatest dispersal potential, S. spathulatus var. attenuatus the smallest, whereas all other taxa were similar. Although useful, dispersal potential alone does not fully explain distributional differences between all range-restricted and widespread taxa, and close assessment of habitat attributes may be required to further elucidate dispersal limitations in some taxa.]]> Fri 17 Jun 2022 17:38:12 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33223 Fri 14 Sep 2018 09:19:07 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46098 Fri 11 Nov 2022 11:26:33 AEDT ]]>